Anabolic steroid use in medical practice
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Testosterone is rapidly absorbed and degraded causing researchers to search for a more stable chemical with a longer bioavailabilty. This search has resulted in three main classes of analogs of testosterone. Class A is made up of the analogs produced by the esterification of the 17(beta)-hydroxyl group with any of the several carboxylic acid groups. Longer carbon chain carboxylic acids yield chemicals which are more lipid soluble. Consequently, these chemicals, when suspended in oil, are perfect for injection. Class B consists of those chemicals that have been alkylated at the 17(alpha) position, such as methyltestosterone. Class C medications are modifications of the Class A and B chemicals. Alkylated and modified ring structures are not metabolized by the liver as quickly as testosterone and are more appropriate for oral administration